![]() Knockdown of mmu-miR-342-3p promoted the expression of Gfap in the activated HSCs in vitro. Moreover, mmu-miR-342-3p expression was negatively correlated with its target gene Zbtb7a in HSCs during E. ![]() We further showed that mmu-miR-342-3p was able to bind to the 3’ UTR of the Zbtb7a gene and regulated its expression. Here, we reported that mmu-miR-342-3p was most dominantly expressed in HSCs and was upregulated in the HSCs in response to E. multilocularis infection-induced liver fibrosis remains largely unclear. However, the molecular mechanism of HSC activation in the E. ![]() ![]() The activation of hepatic stellate cells (HSCs) is a key event in the development of liver fibrosis. Liver fibrosis is one of the histopathological characters during Echinococcus multilocularis infection. ![]()
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